Is there male menopause? Many men believe, that this concept was invented by women. In fact, it isn`t. Andropause is real process, which takes place in male body. Click here to find more information https://medbroadcast.com/condition/getcondition/andropause/.
Changes in male reproductive system during aging
Traditionally, human aging is associated with body reproductive function decrease. For middle-aged women, menopause onset characterizes an end of reproductive period and decrease in sex hormones level leads to various climacteric disorders appearance: vegetovascular and mental reactions, urinary disorders, as well as increase in risk of cardiovascular diseases developing, decrease in bone density.
Recently, great strides have been made in menopausal disorders treatment and prevention, which can significantly reduce incidence of cardiovascular diseases and osteoporosis, as well as improve life quality for women of appropriate age.
Unlike women, men don`t have sharp end to reproductive function. However, it is now generally accepted, that men have gradual decrease in sex hormones level (testosterone in first place), which began at age of 30–40 years. By analogy with cessation of women menstruation – menopause – term “andropause” was introduced to refer to decrease in level of sex hormones for men. We will use term “andropause” to denote not only age-related decline in level of sex hormones, but also clinical manifestations of androgen deficiency (male sex hormones) in old age.
It is noted, that after 30–40 years, testosterone level decreases by about 1–2% per year. In men aged 80 years, testosterone levels average around 40% of normal hormone levels for man of 25 years.
Male hormonal activity level is influenced greatly by many factors. The most notable are:
- Genetic predisposition.
- Body mass index (the “rounder” man is, the closer his andropause).
- Atherosclerosis (in those with coronary insufficiency, androgens level is 5–7% lower). For more details use this link https://en.wikipedia.org/wiki/Atherosclerosis.
- Smoking (smokers lose positions 7–10% faster than non-smokers).
But main men problem is that they are more frivolous than women, belong to their own health.
Main amount (more than 98%) of testosterone circulates in bound state with blood proteins, and only about 1-2% of testosterone is in unbound, free form. It is believed, that biologically active, or bioavailable fraction of testosterone is free circulating fraction. With age, level of biologically active testosterone decreases to greater extent, than level of total testosterone. It has been established, that in 50% of men aged 50–70 years, bioavailable testosterone level is below normal level of hormone for men aged 20–40 years.
In many men, level of female sex hormones (estrogens) increases with age, which leads to change ratio of estrogens in body and specific symptoms appearance (for example, gynecomastia – mammary glands growth).
In men older than 60 years, sperm is often reduced, as well as number of active sperm.